A new study found that adult sleepwalking is a potentially serious condition that may induce violent behaviors and affect health-related quality of life.

“We found a higher frequency of daytime sleepiness, fatigue, insomnia, depressive and anxiety symptoms, and altered quality of life in patients with sleepwalking compared to the control group,” said Yves Dauvilliers, MD, PhD, the study’s principal investigator and lead author. Dauvilliers is professor of physiology and neurology and director of the sleep lab at Gui-de-Chauliac Hospital in Montpellier, France. “What would usually be considered a benign condition, adult sleepwalking is a potentially serious condition and the consequences of sleepwalking episodes should not be ignored.”

Results show that 22.8% of sleepwalkers presented with nightly episodes and 43.5% presented with weekly episodes. Additionally, a positive history of violent sleep-related behaviors was found in 58%, including 17% who experienced at least one episode involving injuries to the sleepwalker or bed partner that required medical care. Reported injuries included bruises, nose bleeds, and fractures, and one participant had sustained multiple fractures and serious head trauma after jumping out of a third-floor window.

According to the authors, this is the largest prospective cohort study on adult sleepwalkers seen in a clinic, using face-to-face clinical interviews, standardized questionnaires, and objective assessment by polysomnography to investigate the clinical characteristics, consequences, and comorbidities of sleepwalking.

The study, appearing in the March issue of the journal SLEEP, involved a prospective case-control study of 100 adult patients in whom primary sleepwalking was diagnosed from June 2007 to January 2011. Exclusion criteria included a positive clinical history of REM sleep behavior disorder (RBD), a similar parasomnia that involves violent dream-related behaviors emerging during REM sleep. The age of the sleepwalkers ranged from 18 to 58 years with a median age of 30. Results were compared with 100 healthy control subjects.

Triggering factors that increased both the frequency and severity of episodes were reported in 59%, related mainly to stressful events, strong positive emotions, and sleep deprivation, and less frequently to drug or alcohol intake or intense evening physical activity. All of these factors promote increased slow wave sleep (SWS) and NREM sleep instability.

“Sleepwalking is an underdiagnosed condition that may be clearly associated with daytime consequences and mood disturbances leading to a major impact on quality of life,” said Dauvilliers. “The burden of sleepwalking in adults needs to be highlighted and emphasized.”