FDA Approves HETLIOZ for Sleep Disturbances in Smith-Magenis Syndrome
Smith-Magenis Syndrome is a rare neurodevelopmental disorder, a defining feature of which is an "inverted" circadian rhythm.
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How Benzos Act on Receptors in the Brain
The GABAA receptor is particularly sensitive to its surrounding environment and has the ability to change conformation in different ways based on the binding of different drugs.
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Narcolepsy May Not Look the Way You Would Expect
Narcolepsy, a relatively rare and poorly understood neurological condition, can be hard to diagnose. Julea Steiner was misdiagnosed for years before a sleep study helped doctors recognize her symptoms—excessive daytime sleepiness, vivid dreams, hallucinations, and mild cataplexy—as narcolepsy.
A Newly Available Drug for Insomnia Addresses Both Sleep Onset and Maintenance
DAYVIGO targets orexin receptors to facilitate sleep. It’s been trialed in the elderly and in patients with common comorbidities.
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FDA Approves Low Sodium Narcolepsy Oral Solution
Marketed by Jazz Pharmaceuticals, Xywav is for the treatment of cataplexy or excessive daytime sleepiness in patients 7 years of age and older with narcolepsy.
Read MoreIn France, Zolpidem Prescriptions Down After Secure Prescribing Form Rule Implemented
This decline was partially compensated for by a rise in the use of a nonbenzodiazepine drug called zopiclone.
Read MoreHow To Know If You’re Relying Too Much On Sleep And Anxiety Medications
Benzodiazepines and prescription sleep aids should not be the first resort and they are not meant for long-term, emphasizes Lifehacker Australia.
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Wakix Efficacy and Safety Abstracts Available on AAN’s Science Highlights Virtual Platform
“These data on the efficacy and safety of WAKIX strengthen the body of scientific evidence that supports WAKIX as a potential treatment option for adult patients living with narcolepsy.”
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Insomnia Medication Prescriptions Increase with Spread of Coronavirus
Research from Express Scripts reveals the coronavirus is making a significant impact on mental health.
Read MorePaper Reviews Mechanisms of Action of Medications for Narcolepsy
Sleep Medicine has published an article that reviews the mechanism of action of available treatments for patients with narcolepsy.
Read MoreSolriamfetol Improves Quality of Life in People With Narcolepsy
Solriamfetol, a dopamine and norepinephrine reuptake inhibitor, offers short-term improvements in health-related quality of life (HRQoL), and work productivity in people with narcolepsy, according to study results published in Sleep Medicine.
Read MoreIs the Antidepressant Trazodone Safe for Insomnia Patients?
The antidepressant trazodone is commonly prescribed to treat insomnia. An article by Consumer Reports looks into the safety of this practice. A handful of studies have shown that trazodone may improve sleep during the first...
Read MoreThe Truth About Sleep Medications: Consumer Reports
Prescription sleep medication may only increase sleep time by about 20 to 30 minutes. All prescription sleep medications come with risks, including drowsiness the next day. Some have also been linked to sleepwalking and...
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Insomnia and Alzheimer’s Disease: A New Randomized Trial Provides Data on the Efficacy and Safety of BELSOMRA (suvorexant) C-IV
The Merck-funded trial brought patients into the sleep lab to determine whether total sleep time...
Read MoreChronic Opioids and Sleep: What Prescribers Need to Know
There are a lot of issues with sleep going unnoticed, reports MedPage Today.”Poor sleep highlights pain. It makes pain worse and makes you more sensitized to pain, and you might take more opioids to alleviate that...
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Prescribing Info Update: BELSOMRA Improves Total Sleep Time, WASO in Study of Mild-to-Moderate Alzheimer’s Disease Patients
Merck has received approval from the U.S. Food and Drug Administration (FDA) for an update to the...
Read MoreJazz Submits NDA for Lower-Sodium Narcolepsy Investigational Drug
Jazz Pharmaceuticals plc submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) on January 21, 2020, seeking marketing approval for JZP-258, an investigational medicine for the treatment of...
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Survey: Your Narcolepsy Patients Don’t Necessarily Agree That Their Symptoms Are Controlled
Investigators surveyed health care providers as well as people with narcolepsy, and multiple...
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