People with severe sleep apnea may have an increased risk of silent strokes and small lesions in the brain, according to a small study presented at the American Stroke Association’s International Stroke Conference 2012.

"We found a surprisingly high frequency of sleep apnea in patients with stroke that underlines its clinical relevance as a stroke risk factor," said Jessica Kepplinger, MD, the study’s lead researcher and stroke fellow in Dresden University Stroke Center’s Department of Neurology at the University of Technology in Dresden, Germany.

"Sleep apnea is widely unrecognized and still neglected. Patients who had severe sleep apnea were more likely to have silent strokes, and the severity of sleep apnea increased the risk of being disabled at hospital discharge."

The researchers found:
• 91% (51 of 56) of the patients who had a stroke had sleep apnea and were more likely to have silent strokes and white matter lesions that increased risk of disability at hospital discharge.
• Having more than five sleep apnea episodes per night was associated with silent strokes.
• More than one-third of patients with white matter lesions had severe sleep apnea and more than 50% of silent stroke patients had sleep apnea.
• Even though men were more likely to have silent infarcts, correlations between sleep apnea and silent infarcts remained the same after adjustment for such gender differences.