HCP Live: Investigators observed that children with sickle cell disease (SCD) may be at an increased risk of comorbid events associated with sleep-disordered breathing (SDB).
The findings, from a team of investigators at the University Hospital of Udine in Italy, showed that progression from the common pediatric sickle cell-associated sleep condition could include hypoxemia, obstructive sleep apnea (OSA), and severe cardiovascular or neurological outcomes.
The study focuses on the epidemiology, clinical presentation, complications, and management of sleep-disordered breathing in children with sickle cell disease. Investigators screened a total of 190 research papers on sleep-disordered breathing in children with sickle cell disease published between 2000-2020, and narrowed the selection to include 62 studies in their analysis.
