Snoring is associated with increased risk of cerebral events in patients with obstructive sleep apnea (OSA) and established cardiovascular disease (CVD), according to study results published in Chest.
Study researchers sought to determine the associations of snoring patterns and major cardiovascular (CV) events relative to OSA. The study was a collection of post-hoc analyses of de-identified participant data from the Sleep Apnea cardioVascular Endpoints (SAVE) study (ClinicalTrials.gov Identifier: NCT00738179).
In total, the primary analysis included 2687 participants with co-existing moderate-to-severe OSA and established coronary or cerebrovascular CVD. All patients were randomly assigned to treatment with either continuous positive airway pressure (CPAP) plus usual care or usual care alone. Patient follow-up occurred at a median of 3.5 years.