A rigorous review of research, led by the University of Southampton, has found there is not enough evidence to support the current clinical practice of prescribing antidepressants for insomnia, reports Medical Xpress.

Part-funded by the NIHR School for Primary Care Research, the review, published in the Cochrane Systematic Reviews Library, re-examined 23 previous studies involving a total of 2,806 patients with insomnia.

The researchers found that, overall, evidence supporting the use of antidepressants for people with sleep problems is of low quality – partly due to the small number of people in individual studies and partly due to how the studies were undertaken and reported.

Some low quality evidence was identified supporting short term (weeks, rather than months) use of some antidepressants, but no evidence was found for amitriptyline, which is commonly used in clinical practice. There was also no evidence to support long-term antidepressant use for insomnia