Insomnia has been identified as an objective sign of an increased risk of developing age-related macular degeneration, reports MD Magazine.

“This study provides large-scale, population-based evidence that insomnia is an independent indicator for the increased risk of subsequent AMD development,” Tsai and colleagues wrote. They also noted that in previous literature, “urinary 6-sulfatoxymelatonin levels, [a] major metabolite of melatonin, in AMD patients were 40% lower than in age-matched controls.”